lauren o'neil


Lauren O'Neil

Assistant Professor of Chemistry

Stratton 301

Lauren O'Neil

"If you teach people the fundamentals, then you’ve given them the opportunity to apply them to whatever situation they come upon."

Whether she is helping students find summer research programs or designing a lab experiment to fit the interests of a given class, Professor O’Neil works tirelessly to present new opportunities for her students. Each year, she tasks members of her Organic Chemistry class with completing an in-depth laboratory project that serves as an introduction to more independent research. After instructing her first class at Wells to synthesize aspirin, she has now tailored the project to reflect the students’ growing interest in environmental issues by challenging students to create ethanol from waste materials, such as newspaper. O’Neil and her fellow science faculty encourage exploration into the historical and cultural contexts of scientific discoveries.


2003 B.S. St. John Fisher College
2008 Ph.D. University of Notre Dame

Select Publications

O’Neil, L.L.; Wiest, O. “Structures and Energetics of Base Flipping of the Thymine Dimer Depend upon DNA Sequence,” The Journal of Physical Chemistry B. 2008, 112, 4113-4122.

O’Neil, L.L.; Wiest, O. “Sequence Dependence in Base Flipping: Experimental and Computational Studies,” Organic and Biomolecular Chemistry 2008, 6, 485-492.

O’Neil, L.L.; Grossfield, A.; Wiest, O. “Base Flipping of Thymine Dimer in Duplex DNA,” The Journal of Physical Chemistry B. 2007, 111, 11843-11849.

O’Neil, L.L.; Wiest, O. “Acyclic or Long-bond Intermediate in the ETC Dimerization of 4-Methoxystyrene,” The Journal of Organic Chemistry. 2006, 71, 8926-8933.
O’Neil, L.L.; Wiest, O. “A Selective, Noncovalent Assay for Base Flipping in DNA,” Journal of the American Chemical Society. 2005, 127, 16800-16801.

Harrison, C.B.; O’Neil, L.L.; Wiest, O. “Computational Studies of DNA Photolyase,” The Journal of Physical Chemistry A, 2005, 109, 7001-7012.

Courses Taught

  • Organic Chemistry I and II
  • Biochemistry
  • Forensic Science
  • Medicinal Chemistry
  • Biochemical Pathways